Who doesn't have excess stuff they need to get rid of? A lot of people make money on the internet by opening up an eBay auction site and selling things from their home.
With this method, no website is needed. All you need to do is sign up for an eBay account and go from there.
I won't even pretend to be an expert on this subject. I'm an affiliate marketer at heart so I'll let the eBay experts have this one.
Speaking of experts, John Thornhill wrote a book on how to profit off eBay and become a successful PowerSeller like he did.
You may find this book useful if this is the approach you want to take. Nothing like learning from someone who has actually been there, done that.