If you have experience or skills then one of the best ways to make money is by providing niche industry wisdom and expert advice. It doesn't matter what industry you are in.
Start blogging about what you know. Offer to help people by providing knowledge. Answer questions on other sites, blogs and forums.
Once people recognize you as an expert they will trust you, and you can start leveraging that trust to make money by offering services and consulting in your niche. What's nice about this idea is that there's nothing stopping you providing consulting facilities online - via Skype or a Google+ hangout.
Depending what industry you're in, you might be able to operate completely from home without having to make expensive trips out to clients. For example, a technology consultant for small businesses run by baby-boomers could be a fantastic moneyspinner.